The graph below ranks each South Carolina County by total residents according to the 2012 census estimates.
South Carolina total population by county
| County | Total Population |
| Greenville |  466,772 |
| Richland | 393,853 |
| Charleston | 365,170 |
| Spartanburg | 288,583 |
| Horry | 282,024 |
| Lexington | 270,272 |
| York | 234,608 |
| Berkeley | 189,837 |
| Anderson | 189,357 |
| Beaufort | 168,016 |
| Aiken | 163,299 |
| Dorchester | 142,490 |
| Florence | 137,939 |
| Pickens | 119,745 |
| Sumter | 108,127 |
| Orangeburg | 91,399 |
| Lancaster | 79,153 |
| Oconee | 74,628 |
| Greenwood | 69,800 |
| Darlington | 68,178 |
| Laurens | 66,234 |
| Kershaw | 62,200 |
| Georgetown | 60,240 |
| Cherokee | 55,760 |
| Chesterfield | 46,151 |
| Colleton | 38,211 |
| Newberry | 37,587 |
| Clarendon | 34,367 |
| Williamsburg | 33,581 |
| Chester | 32,615 |
| Marion | 32,414 |
| Dillon | 31,451 |
| Union | 28,273 |
| Marlboro | 28,141 |
| Edgefield | 26,389 |
| Jasper | 25,879 |
| Abbeville | 25,071 |
| Fairfield | 23,338 |
| Barnwell | 22,271 |
| Hampton | 20,738 |
| Saluda | 19,940 |
| Lee | 18,632 |
| Bamberg | 15,777 |
| Calhoun | 14,928 |
| Allendale | 10,003 |
| McCormick | 9,976 |