| County | Mixed Race Population |
| Pennington |  2,443 |
| Minnehaha | 2,051 |
| Meade | 569 |
| Lincoln | 359 |
| Brown | 326 |
| Bennett | 253 |
| Shannon | 242 |
| Codington | 240 |
| Lawrence | 237 |
| Hughes | 235 |
| Todd | 211 |
| Fall River | 199 |
| Butte | 179 |
| Davison | 178 |
| Yankton | 177 |
| Brookings | 170 |
| Beadle | 170 |
| Clay | 163 |
| Roberts | 156 |
| Moody | 154 |
| Custer | 144 |
| Charles Mix | 138 |
| Dewey | 95 |
| Corson | 93 |
| Union | 92 |
| Walworth | 81 |
| Lyman | 78 |
| Mellette | 73 |
| Day | 72 |
| Tripp | 71 |
| Jackson | 63 |
| Brule | 61 |
| Spink | 54 |
| Lake | 51 |
| Gregory | 50 |
| Turner | 49 |
| Stanley | 45 |
| Ziebach | 40 |
| Deuel | 36 |
| Bon Homme | 35 |
| Hutchinson | 35 |
| Buffalo | 34 |
| Hamlin | 32 |
| Marshall | 30 |
| Haakon | 28 |
| Kingsbury | 28 |
| Grant | 27 |
| Perkins | 23 |
| McCook | 20 |
| Sully | 20 |
| Douglas | 20 |
| Jones | 18 |
| Potter | 17 |
| Hanson | 14 |
| Clark | 13 |
| Hand | 12 |
| Hyde | 12 |
| Edmunds | 10 |
| Aurora | 9 |
| Miner | 8 |
| Sanborn | 6 |
| Faulk | 6 |
| McPherson | 6 |
| Campbell | 5 |
| Jerauld | 5 |
| Harding | 5 |